While the exact cause for colorectal cancer is unknown, there are certain factors that may increase the risk of developing colorectal cancer. Some of these factors are:
- Age - Colorectal cancer usually affects people over the age of 50.
History - Patients with
- History of polyps.
- History of endometrial cancer and being a carrier for the MMR gene mutation in women
- Inherited syndromes - Familial Adenomatous Polyposis (FAP) and Lynch syndrome also known as Hereditary Non Polyposis Colorectal Cancer (HNPCC).
- Inflammatory intestinal conditions - Ulcerative colitis and Crohn's disease
- Hormone Replacement Therapy (HRT) - In post-menopausal women
- Family history of colorectal cancer.
- Exposure to radiation - Radiation to treat previous cancers in the abdominal region.
- Diabetes - People with diabetes or insulin resistance
Lifestyle factors such as
- Low-fiber, high-fat diet
- Sedentary lifestyle