Bone and Soft Tissue Oncology

Bone and Soft Tissue Oncology

Sarcomas are malignancies of connective tissue, e.g., bone, cartilage, skeletal or smooth muscle, fibroblasts, fat cells, blood vessels. They may occur at any age. Specific sarcomas are characteristic of different age groups, and given the number of different types of tissues involved, it is not surprising that there are at least 70 different histological types of sarcoma.

Around half of sarcomas occur in the lower extremity, but any site in the body from the scalp to the toes may be affected.

  • About half of bone and soft tissue sarcomas begin in an arm or leg
  • Around 40 per cent start in the torso or belly
  • About 10 per cent start in the head or neck


Types of Bone and soft Tissue Sarcomas:


Many different types of bone or soft tissue sarcomas can develop and affect the tissues.

  • Angiosarcoma affects the blood or lymph vessels.
  • Chordoma forms in the spinal cord.
  • Chondrosarcoma forms in cartilage.
  • Ewing sarcoma develop in children in bone or soft tissue.
  • Fibrosarcoma forms in fibroblasts, common cells in connective tissue.
  • Gastrointestinal stromal tumor (GIST) affects the digestive tract.
  • Liposarcoma forms in fat cells.
  • Myxofibrosarcoma forms in connective tissue.
  • Osteosarcoma develops in bone, one of the most common types of bone sarcoma.
  • Rhabdomyosarcoma forms in skeletal muscle.
  • Bone cancer starts in the bone, as opposed to spreading from an organ to the bones.
  • Soft tissue sarcoma starts in connective tissue.